Tumor cell plasticity, heterogeneity, and resistance in crucial microenvironmental niches in glioma
Whether the perivascular niche (PVN) and the integration into multicellular networks by tumor microtubes (TMs) have a different role in glioblastoma progression and resistance to therapies is currently unclear. Here, the authors, by long-term tracking of individual glioma, demonstrate that both nich...
Saved in:
Main Authors: | Erik Jung, Matthias Osswald, Miriam Ratliff, Helin Dogan, Ruifan Xie, Sophie Weil, Dirk C. Hoffmann, Felix T. Kurz, Tobias Kessler, Sabine Heiland, Andreas von Deimling, Felix Sahm, Wolfgang Wick, Frank Winkler |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/a219a87b2e5c41669d28b24deca0d0b9 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity
by: Andreas Heindl, et al.
Published: (2018) -
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas
by: Katrin Aslan, et al.
Published: (2020) -
Glioblastoma multiforme restructures the topological connectivity of cerebrovascular networks
by: Artur Hahn, et al.
Published: (2019) -
Microenvironmental considerations in the application of human mesenchymal stem cells in regenerative therapies
by: Steven J Greco, et al.
Published: (2008) -
Understanding Monoclonal B Cell Lymphocytosis: An Interplay of Genetic and Microenvironmental Factors
by: Chrysi Galigalidou, et al.
Published: (2021)