Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis

In bacteria, the conserved trans-translation system serves as the primary pathway of ribosome rescue, but many species can also use alternative rescue pathways. Here the authors report that in B. subtilis, the rescue factor BrfA binds to non-stop stalled ribosomes, recruits RF2 but not RF1, and indu...

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Autores principales: Naomi Shimokawa-Chiba, Claudia Müller, Keigo Fujiwara, Bertrand Beckert, Koreaki Ito, Daniel N. Wilson, Shinobu Chiba
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/a2679a073e3943e994ac5d75350e424f
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