Delivery of large transgene cassettes by foamy virus vector

Abstract Viral vectors are effective tools in gene therapy, but their limited packaging capacity can be restrictive. Larger clinically-relevant vectors are needed. Foamy viruses have the largest genomes among mammalian retroviruses and their vectors have shown potential for gene therapy in preclinic...

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Autores principales: Nathan Paul Sweeney, Jinhong Meng, Hayley Patterson, Jennifer E. Morgan, Myra McClure
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/a26dc39854a54893898e2bcd915a211e
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