Delivery of large transgene cassettes by foamy virus vector
Abstract Viral vectors are effective tools in gene therapy, but their limited packaging capacity can be restrictive. Larger clinically-relevant vectors are needed. Foamy viruses have the largest genomes among mammalian retroviruses and their vectors have shown potential for gene therapy in preclinic...
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Autores principales: | Nathan Paul Sweeney, Jinhong Meng, Hayley Patterson, Jennifer E. Morgan, Myra McClure |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/a26dc39854a54893898e2bcd915a211e |
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