Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
Polyamines bind to nucleic acids and their function is regulated by reversible acetylation. Here, the authors show that histone deacetylase 10 is a polyamine deacetylase and present its crystal structure with a bound polyamine transition state analogue inhibitor.
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2017
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/a275abbed63b43529d75e158a00c61cf |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|