The signal sequence coding region promotes nuclear export of mRNA.

In eukaryotic cells, most mRNAs are exported from the nucleus by the transcription export (TREX) complex, which is loaded onto mRNAs after their splicing and capping. We have studied in mammalian cells the nuclear export of mRNAs that code for secretory proteins, which are targeted to the endoplasmi...

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Autores principales: Alexander F Palazzo, Michael Springer, Yoko Shibata, Chung-Sheng Lee, Anusha P Dias, Tom A Rapoport
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2007
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Acceso en línea:https://doaj.org/article/a287424096ac43c68485a6fdcd2d525f
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