Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCCSummary
Background & Aims: Activation of the kelch-like ECH-associated protein 1 (Keap1)–nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway has been associated with metabolic reprogramming in many tumors, including hepatocellular carcinoma (HCC). However, the contribution of Nrf2 mutations i...
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Main Authors: | Sandra Mattu, Patrizia Zavattari, Marta Anna Kowalik, Marina Serra, Pia Sulas, Rajesh Pal, Elisabetta Puliga, Salvatore Sutti, Beatrice Foglia, Maurizio Parola, Emanuele Albano, Silvia Giordano, Andrea Perra, Amedeo Columbano |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2022
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Subjects: | |
Online Access: | https://doaj.org/article/a287ac6f649144fb9e8b07c7fac86783 |
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