A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation

Inflammatory diseases of the pancreas are currently untreatable and lack a pre-clinical model that recapitulates the hallmarks of the human pathology. Here, the authors generate a knock-in mouse strain with increased tripsinogen autoactivation and show that it develops spontaneous pancreatic patholo...

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Autores principales: Andrea Geisz, Miklós Sahin-Tóth
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Q
Acceso en línea:https://doaj.org/article/a2962e90a2a946a288e473df4b9941c0
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