A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation
Inflammatory diseases of the pancreas are currently untreatable and lack a pre-clinical model that recapitulates the hallmarks of the human pathology. Here, the authors generate a knock-in mouse strain with increased tripsinogen autoactivation and show that it develops spontaneous pancreatic patholo...
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Acceso en línea: | https://doaj.org/article/a2962e90a2a946a288e473df4b9941c0 |
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