N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection

N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection

Here the authors develop a single molecule array (Simoa) immunoassay for detection of SARS-CoV-2 nucleocapsid protein in venous and dried capillary blood as well as saliva. The assay shows good performance in symptomatic, asymptomatic, and pre-symptomatic PCR+ individuals.

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Bibliographic Details
Main Authors: Dandan Shan, Joseph M. Johnson, Syrena C. Fernandes, Hannah Suib, Soyoon Hwang, Danica Wuelfing, Muriel Mendes, Marcella Holdridge, Elaine M. Burke, Katie Beauregard, Ying Zhang, Megan Cleary, Samantha Xu, Xiao Yao, Purvish P. Patel, Tatiana Plavina, David H. Wilson, Lei Chang, Kim M. Kaiser, Jacob Nattermann, Susanne V. Schmidt, Eicke Latz, Kevin Hrusovsky, Dawn Mattoon, Andrew J. Ball
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
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Online Access:https://doaj.org/article/a29c0aa5590d40f2b3a8c214e47a4425
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