Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation

Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation

The transcription factor, serum response factor, SRF regulates critical smooth muscle (SM) contractile gene expression but what else controls SM differentiation is unclear. Here, Horita et al. demonstrate that nuclear PTEN acts with SRF at the transcriptional level to maintain the differentiated SM...

Full description

Saved in:
Bibliographic Details
Main Authors: Henrick Horita, Christina L. Wysoczynski, Lori A. Walker, Karen S. Moulton, Marcella Li, Allison Ostriker, Rebecca Tucker, Timothy A. McKinsey, Mair E. A. Churchill, Raphael A. Nemenoff, Mary C. M. Weiser-Evans
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Science
Q
Online Access:https://doaj.org/article/a2a037feef7f4c279013ebdd96c7d09b
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/a2a037feef7f4c279013ebdd96c7d09b

Similar Items