Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.
Human herpesvirus 8 (HHV-8) is an oncogenic virus that enters cells by fusion of the viral and endosomal cellular membranes in a process mediated by viral surface glycoproteins. One of the cellular receptors hijacked by HHV-8 to gain access to cells is the EphA2 tyrosine kinase receptor, and the mec...
Enregistré dans:
Auteurs principaux: | Taylor P Light, Delphine Brun, Pablo Guardado-Calvo, Riccardo Pederzoli, Ahmed Haouz, Frank Neipel, Félix A Rey, Kalina Hristova, Marija Backovic |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/a2c619e3194f40bca4563a251b741f12 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker
par: Bernhard C. Lechtenberg, et autres
Publié: (2021) -
Author Correction: The EphA2 receptor is activated through induction of distinct, ligand-dependent oligomeric structures
par: Deo R. Singh, et autres
Publié: (2018) -
Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality
par: Joonas Jukonen, et autres
Publié: (2021) -
Ephrin Receptor A4 is a New Kaposi’s Sarcoma-Associated Herpesvirus Virus Entry Receptor
par: Jia Chen, et autres
Publié: (2019) -
Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10.
par: Peter W Janes, et autres
Publié: (2009)