Designing minimal genomes using whole-cell models

Genome engineering will one day benefit from computational tools that can design genomes with desired functions. Here the authors develop computational design-simulate-test algorithms to design minimal genomes based on the whole-cell model of Mycoplasma genitalium.

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Autores principales: Joshua Rees-Garbutt, Oliver Chalkley, Sophie Landon, Oliver Purcell, Lucia Marucci, Claire Grierson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a2d27e6f513347d0a606d457b9efaf7f
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