Novel giardicidal compounds bearing proton pump inhibitor scaffold proceeding through triosephosphate isomerase inactivation

Abstract Giardiasis is a worldwide parasitic disease that affects mainly children and immunosuppressed people. Side effects and the emergence of resistance over current used drugs make imperative looking for new antiparasitics through discovering of new biological targets and designing of novel drug...

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Autores principales: B. Hernández-Ochoa, G. Navarrete-Vázquez, C. Nava-Zuazo, A. Castillo-Villanueva, S. T. Méndez, A. Torres-Arroyo, S. Gómez-Manzo, J. Marcial-Quino, M. Ponce-Macotela, Y. Rufino-González, M. Martínez-Gordillo, G. Palencia-Hernández, N. Esturau-Escofet, E. Calderon-Jaimes, J. Oria-Hernández, H. Reyes-Vivas
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/a2e2eb22efc4463c908cf0ac908341c3
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