Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages

The molecular mechanisms regulating skin dermal changes are unclear. Here, the authors show that deletion of Hedgehog (Hh) in the upper dermis alters the response to epidermal Wnt signalling, which, together with changes in extracellular matrix production, influences distinct fibroblast lineages dif...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Beate M. Lichtenberger, Maria Mastrogiannaki, Fiona M. Watt
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
Q
Accès en ligne:https://doaj.org/article/a2f00ef4034b4d2ea03277e5251ed944
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!