Cyclosporine Biosynthesis in <italic toggle="yes">Tolypocladium inflatum</italic> Benefits Fungal Adaptation to the Environment
ABSTRACT The cycloundecapeptide cyclosporin A (CsA) was first isolated from the insect-pathogenic fungus Tolypocladium inflatum for its antifungal activity and later developed as an immunosuppressant drug. However, the full biosynthetic mechanism of CsA remains unknown and has puzzled researchers fo...
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| Main Authors: | , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2018
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| Subjects: | |
| Online Access: | https://doaj.org/article/a2fe4496fd814f0592509202ec8e0ef0 |
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