Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice.
Stable integration of HIV proviral DNA into host cell chromosomes, a hallmark and essential feature of the retroviral life cycle, establishes the infection permanently. Current antiretroviral combination drug therapy cannot cure HIV infection. However, expressing an engineered HIV-1 long terminal re...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/a30385a2f1f846a49457496bcee83427 |
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