Deficiency of the Novel Exopolyphosphatase Rv1026/PPX2 Leads to Metabolic Downshift and Altered Cell Wall Permeability in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

ABSTRACT Mycobacterium tuberculosis can persist for decades in the human host. Stringent response pathways involving inorganic polyphosphate [poly(P)], which is synthesized and hydrolyzed by polyphosphate kinase (PPK) and exopolyphosphatase (PPX), respectively, are believed to play a key regulatory...

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Bibliographic Details
Main Authors: Yu-Min Chuang, Nirmalya Bandyopadhyay, Dalin Rifat, Harvey Rubin, Joel S. Bader, Petros C. Karakousis
Format: article
Language:EN
Published: American Society for Microbiology 2015
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Online Access:https://doaj.org/article/a3187c98a97a4104bf853ed7623dc7ae
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