A simple repeat polymorphism in the MITF-M promoter is a key regulator of white spotting in dogs.

A simple repeat polymorphism in the MITF-M promoter is a key regulator of white spotting in dogs.

The white spotting locus (S) in dogs is colocalized with the MITF (microphtalmia-associated transcription factor) gene. The phenotypic effects of the four S alleles range from solid colour (S) to extreme white spotting (s(w)). We have investigated four candidate mutations associated with the s(w) al...

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Autores principales: Izabella Baranowska Körberg, Elisabeth Sundström, Jennifer R S Meadows, Gerli Rosengren Pielberg, Ulla Gustafson, Åke Hedhammar, Elinor K Karlsson, Jennifer Seddon, Arne Söderberg, Carles Vilà, Xiaolan Zhang, Mikael Åkesson, Kerstin Lindblad-Toh, Göran Andersson, Leif Andersson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a3343de64bc3464695558e10d5c445d1
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