Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype

Abstract Senescent cells are capable of expressing a myriad of inflammatory cytokines and this pro-inflammatory phenomenon is known as senescence-associated secretory phenotype (SASP). The contribution of this phenomenon in brain ischemia was scarce. A mouse model of transient focal cerebral ischemi...

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Bibliographic Details
Main Authors: Coral Torres-Querol, Pascual Torres, Noemí Vidal, Manel Portero-Otín, Gloria Arque, Francisco Purroy
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/a33a8c378f5e40299a096dfba4c3232c
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