Thick filament mechano-sensing is a calcium-independent regulatory mechanism in skeletal muscle

Recent data suggest that muscle contraction is regulated by thick filament mechano-sensing in addition to the well-known thin filament-mediated calcium signalling pathway. Here the authors provide direct evidence that myosin activation in skeletal muscle is controlled by thick filament stress indepe...

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Bibliographic Details
Main Authors: L. Fusi, E. Brunello, Z. Yan, M. Irving
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/a33d9371f6e84246a2c0cb6421e371e0
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