Analysis of extracellular mRNA in human urine reveals splice variant biomarkers of muscular dystrophies

Patients with myotonic dystrophy need to undergo invasive muscle biopsies to monitor disease progression and response to therapy. Here, the authors show that extracellular RNAs in human urine can be used as biomarkers to differentiate patients from unaffected controls, and to monitor exon skipping i...

Full description

Saved in:
Bibliographic Details
Main Authors: Layal Antoury, Ningyan Hu, Leonora Balaj, Sudeshna Das, Sofia Georghiou, Basil Darras, Tim Clark, Xandra O. Breakefield, Thurman M. Wheeler
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/a34cd40d232146518807809a9a2dd9f6
Tags: Add Tag
No Tags, Be the first to tag this record!