Rare and potentially pathogenic variants in hydroxycarboxylic acid receptor genes identified in breast cancer cases

Abstract Background Three genes clustered together on chromosome 12 comprise a group of hydroxycarboxylic acid receptors (HCARs): HCAR1, HCAR2, and HCAR3. These paralogous genes encode different G-protein coupled receptors responsible for detecting glycolytic metabolites and controlling fatty acid o...

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Autores principales: Cierla McGuire Sams, Kasey Shepp, Jada Pugh, Madison R. Bishop, Nancy D. Merner
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/a36021b872c5416e9e8ea45993ee6c7e
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