Genetic variation of the ghrelin signalling system in individuals with amphetamine dependence.

The development of amphetamine dependence largely depends on the effects of amphetamine in the brain reward systems. Ghrelin, an orexigenic peptide, activates the reward systems and is required for reward induced by alcohol, nicotine, cocaine and amphetamine in mice. Human genetic studies have shown...

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Autores principales: Petra Suchankova, Elisabet Jerlhag, Nitya Jayaram-Lindström, Staffan Nilsson, Kjell Toren, Annika Rosengren, Jörgen A Engel, Johan Franck
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/a3668e1171f34b20833392811df04f45
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