The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1
Abstract Background DLC1, a tumor suppressor gene that is downregulated in many cancer types by genetic and nongenetic mechanisms, encodes a protein whose RhoGAP and scaffolding activities contribute to its tumor suppressor functions. The role of the DLC1 START (StAR-related lipid transfer; DLC1-STA...
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Autores principales: | , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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BMC
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/a367e3987a09471bbf53fecd07797e4f |
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