Determination of pharmacokinetic parameters and tissue distribution characters of enrofloxacin and its metabolite ciprofloxacin in Procambarus clarkii after two routes of administration

Enrofloxacin (ENR) is widely used for treatment and prevention of bacterial pathogen infections in aquatic animals. However, limited knowledge on kinetic disposal process of ENR in crayfish (Procambrus clarkii). Therefore, the objective of this study was to explore the pharmacokinetics (PK) and tiss...

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Autores principales: Yong-Tao Liu, Guo-Dong Zhang, Ru-Yu Sun, Shu Zhou, Jing Dong, Yi-Bin Yang, Qiu-Hong Yang, Ning Xu, Xiao-Hui Ai
Formato: article
Lenguaje:EN
Publicado: Elsevier 2022
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Acceso en línea:https://doaj.org/article/a38392ad8100416d8cf15a07cf304ac4
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