Four amino acids within a tandem QxVx repeat in a predicted extended α-helix of the Smad-binding domain of Sip1 are necessary for binding to activated Smad proteins.
The zinc finger transcription factor Smad-interacting protein-1 (Sip1; Zeb2, Zfhx1b) plays an important role during vertebrate embryogenesis in various tissues and differentiating cell types, and during tumorigenesis. Previous biochemical analysis suggests that interactions with several partner prot...
Guardado en:
Autores principales: | Andrea Conidi, Veronique van den Berghe, Kris Leslie, Agata Stryjewska, Hua Xue, Ye-Guang Chen, Eve Seuntjens, Danny Huylebroeck |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/a38d0dea782f40bb94b8e06367a20dfe |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Knockdown of circSMAD2 inhibits the tumorigenesis of gallbladder cancer through binding with eIF4A3
por: Yiyu Qin, et al.
Publicado: (2021) -
Epigenetic Modulation of Class-Switch DNA Recombination to IgA by miR-146a Through Downregulation of Smad2, Smad3 and Smad4
por: Paolo Casali, et al.
Publicado: (2021) -
Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis
por: Diana Monsivais, et al.
Publicado: (2021) -
Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity
por: Meng Xia, et al.
Publicado: (2017) -
The ChiS-Family DNA-Binding Domain Contains a Cryptic Helix-Turn-Helix Variant
por: Catherine A. Klancher, et al.
Publicado: (2021)