DNA gyrase could be a crucial regulatory factor for growth and survival of Mycobacterium leprae

Abstract Leprosy, an important infectious disease in humans caused by Mycobacterium leprae (Mle), remains endemic in many countries. Notably, the pathogen cannot be cultured in vitro, except in mouse footpads in vivo. The molecular basis of these characteristics and the mechanisms remain unknown. Co...

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Autores principales: Hyun Kim, Yasuo Fukutomi, Chie Nakajima, Youn Uck Kim, Shigetarou Mori, Keigo Shibayama, Noboru Nakata, Yasuhiko Suzuki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/a3a72a913ac349d5ac56b35039dcfd52
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