SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas.

Squamous cell carcinoma (SCC) of the lung is a frequent and aggressive cancer type. Gene amplifications, a known activating mechanism of oncogenes, target the 3q26-qter region as one of the most frequently gained/amplified genomic sites in SCC of various types. Here, we used array comparative genomi...

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Autores principales: Thomas Hussenet, Soraya Dali, Julien Exinger, Ben Monga, Bernard Jost, Doulaye Dembelé, Nadine Martinet, Christelle Thibault, Joerg Huelsken, Elisabeth Brambilla, Stanislas du Manoir
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/a3b2ea6dd9484143b1b61997e717f532
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