SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas.

SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas.

Squamous cell carcinoma (SCC) of the lung is a frequent and aggressive cancer type. Gene amplifications, a known activating mechanism of oncogenes, target the 3q26-qter region as one of the most frequently gained/amplified genomic sites in SCC of various types. Here, we used array comparative genomi...

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Autores principales: Thomas Hussenet, Soraya Dali, Julien Exinger, Ben Monga, Bernard Jost, Doulaye Dembelé, Nadine Martinet, Christelle Thibault, Joerg Huelsken, Elisabeth Brambilla, Stanislas du Manoir
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a3b2ea6dd9484143b1b61997e717f532
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