Diversity-oriented synthesis of glycomimetics

Glycomimetics are structural mimics of carbohydrates that can replicate their biological activity but have improved drug-like properties. Here, using proline-catalysed α-halogenation/aldol cascades, carbohydrate building blocks are readily assembled and then diversified into glycomimetics including...

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Bibliographic Details
Main Authors: Michael Meanwell, Gaelen Fehr, Weiwu Ren, Bharanishashank Adluri, Victoria Rose, Johannes Lehmann, Steven M. Silverman, Rozhin Rowshanpour, Christopher Adamson, Milan Bergeron-Brlek, Hayden Foy, Venugopal Rao Challa, Louis-Charles Campeau, Travis Dudding, Robert Britton
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/a3c44d6cc42a4edc9776c757309987ae
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