Molecular Mechanism of SR Protein Kinase 1 Inhibition by the Herpes Virus Protein ICP27

ABSTRACT Serine-arginine (SR) protein kinase 1 (SRPK1) catalyzes the phosphorylation of SR proteins, which are a conserved family of splicing factors that contain a domain rich in arginine and serine repeats. SR proteins play important roles in constitutive pre-mRNA splicing and are also important r...

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Bibliographic Details
Main Authors: Richard B. Tunnicliffe, William K. Hu, Michele Y. Wu, Colin Levy, A. Paul Mould, Edward A. McKenzie, Rozanne M. Sandri-Goldin, Alexander P. Golovanov
Format: article
Language:EN
Published: American Society for Microbiology 2019
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Online Access:https://doaj.org/article/a3d1cf2d127e48568e7e7049c2934cf3
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