Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies

Abstract Microphysiological systems (MPS), consisting of tissue constructs, biomaterials, and culture media, aim to recapitulate relevant organ functions in vitro. MPS components are housed in fluidic hardware with operational protocols, such as periodic complete media replacement. Such batch-like o...

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Bibliographic Details
Main Authors: Christian Maass, Matthew Dallas, Matthew E. LaBarge, Michael Shockley, Jorge Valdez, Emily Geishecker, Cynthia L. Stokes, Linda G. Griffith, Murat Cirit
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/a3e52ad9c3af416aad7fb8fc0c9a0240
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