Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies

Abstract Microphysiological systems (MPS), consisting of tissue constructs, biomaterials, and culture media, aim to recapitulate relevant organ functions in vitro. MPS components are housed in fluidic hardware with operational protocols, such as periodic complete media replacement. Such batch-like o...

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Autores principales: Christian Maass, Matthew Dallas, Matthew E. LaBarge, Michael Shockley, Jorge Valdez, Emily Geishecker, Cynthia L. Stokes, Linda G. Griffith, Murat Cirit
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a3e52ad9c3af416aad7fb8fc0c9a0240
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