KSHV microRNAs mediate cellular transformation and tumorigenesis by redundantly targeting cell growth and survival pathways.

Kaposi's sarcoma-associated herpesvirus (KSHV) is causally linked to several human cancers, including Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease, malignancies commonly found in HIV-infected patients. While KSHV encodes diverse functional products,...

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Auteurs principaux: Rosalie Moody, Ying Zhu, Yufei Huang, Xiaodong Cui, Tiffany Jones, Roble Bedolla, Xiufen Lei, Zhiqiang Bai, Shou-Jiang Gao
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/a3e5e02a4aab4aa4af5ea1e4cffdfbd1
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