Enantioselective three-component aminomethylation of α-diazo ketones with alcohols and 1,3,5-triazines

Strategies for enantioselective α-aminomethylation of carbonyl compounds rely on the chiral activation of stable ketones substrate. Here, the authors report a rhodium/chiral phosphoric acid cooperative catalysis for the three-component reaction of α-diazo ketones with alcohols and 1,3,5-triazines vi...

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Autores principales: Jiuwei Che, Li Niu, Shikun Jia, Dong Xing, Wenhao Hu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a3ef597d4cc44ac5b8b287977fd5add3
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