Input-dependent synaptic suppression by pregabalin in the central amygdala in male mice with inflammatory pain
Pregabalin (PGB) is a synthetic amino acid compound most widely prescribed for chronic peripheral and central neuropathic pain. PGB is a ligand for the α2δ1 subunit of voltage-dependent calcium channels, and its binding reduces neurotransmitter release and thus inhibits synaptic transmission. The ce...
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Main Authors: | Sumii Yamamoto, Yukari Takahashi, Fusao Kato |
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Format: | article |
Language: | EN |
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Elsevier
2021
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Online Access: | https://doaj.org/article/a42f59f715894d319de74b5616f5685c |
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