Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks

Spatial information in the tumour microenvironment may be exploited to optimise diagnosis, prognosis and therapy. Here, the authors develop a spatial analytics computational and systems pathology platform (SpAn) based on highly multiplexed antibody imaging on colorectal cancer samples to infer emerg...

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Bibliographic Details
Main Authors: Shikhar Uttam, Andrew M. Stern, Christopher J. Sevinsky, Samantha Furman, Filippo Pullara, Daniel Spagnolo, Luong Nguyen, Albert Gough, Fiona Ginty, D. Lansing Taylor, S. Chakra Chennubhotla
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/a43bb54843794cb1bbe267661f6d6f4c
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