Benznidazole Anti-Inflammatory Effects in Murine Cardiomyocytes and Macrophages Are Mediated by Class I PI3Kδ

Benznidazole (Bzl), the drug of choice in many countries for the treatment of Chagas disease, leads to parasite clearance in the early stages of infection and contributes to immunomodulation. In addition to its parasiticidal effect, Bzl inhibits the NF-κB pathway. In this regard, we have previously...

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Auteurs principaux: Ágata C. Cevey, Paula D. Mascolo, Federico N. Penas, Azul V. Pieralisi, Aldana S. Sequeyra, Gerardo A. Mirkin, Nora B. Goren
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/a448a705e0d847578212886c8a173008
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