Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response

Lipid droplets (LDs) are recognized as dynamic organelles and scaffolding platforms to regulate signalling cascades. Here, Monson et al. provide evidence that LDs are involved in regulation of an early antiviral immune response specifically through the enhanced modulation of IFN following viral infe...

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Autores principales:	E. A. Monson, K. M. Crosse, M. Duan, W. Chen, R. D. O’Shea, L. M. Wakim, J. M. Carr, D. R. Whelan, K. J. Helbig
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a47b935581e943e1b380272d0fcf2184
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spelling	oai:doaj.org-article:a47b935581e943e1b380272d0fcf21842021-12-02T18:37:05ZIntracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response10.1038/s41467-021-24632-52041-1723https://doaj.org/article/a47b935581e943e1b380272d0fcf21842021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24632-5https://doaj.org/toc/2041-1723Lipid droplets (LDs) are recognized as dynamic organelles and scaffolding platforms to regulate signalling cascades. Here, Monson et al. provide evidence that LDs are involved in regulation of an early antiviral immune response specifically through the enhanced modulation of IFN following viral infection in vitro and in vivo.E. A. MonsonK. M. CrosseM. DuanW. ChenR. D. O’SheaL. M. WakimJ. M. CarrD. R. WhelanK. J. HelbigNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q E. A. Monson K. M. Crosse M. Duan W. Chen R. D. O’Shea L. M. Wakim J. M. Carr D. R. Whelan K. J. Helbig Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response
description	Lipid droplets (LDs) are recognized as dynamic organelles and scaffolding platforms to regulate signalling cascades. Here, Monson et al. provide evidence that LDs are involved in regulation of an early antiviral immune response specifically through the enhanced modulation of IFN following viral infection in vitro and in vivo.
format	article
author	E. A. Monson K. M. Crosse M. Duan W. Chen R. D. O’Shea L. M. Wakim J. M. Carr D. R. Whelan K. J. Helbig
author_facet	E. A. Monson K. M. Crosse M. Duan W. Chen R. D. O’Shea L. M. Wakim J. M. Carr D. R. Whelan K. J. Helbig
author_sort	E. A. Monson
title	Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response
title_short	Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response
title_full	Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response
title_fullStr	Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response
title_full_unstemmed	Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response
title_sort	intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a47b935581e943e1b380272d0fcf2184
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_version_	1718377878716940288

Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response

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