The in utero programming effect of increased maternal androgens and a direct fetal intervention on liver and metabolic function in adult sheep.
Epigenetic changes in response to external stimuli are fast emerging as common underlying causes for the pre-disposition to adult disease. Prenatal androgenization is one such model that results in reproductive and metabolic features that are present in conditions such as polycystic ovary syndrome (...
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Auteurs principaux: | Kirsten Hogg, Charlotte Wood, Alan S McNeilly, W Colin Duncan |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/a497d4ab59ff47b5bf2a68e477119ae3 |
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