Rational Design of Simple Organocatalysts for the HSiCl<sub>3</sub> Enantioselective Reduction of (E)-<i>N</i>-(1-Phenylethylidene)aniline

Prolinamides are well-known organocatalysts for the HSiCl<sub>3</sub> reduction of imines; however, custom design of catalysts is based on trial-and-error experiments. In this work, we have used a combination of computational calculations and experimental work, including kinetic analyses...

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Bibliographic Details
Main Authors: María Maciá, Raúl Porcar, Vicente Martí-Centelles, Eduardo García-Verdugo, Maria Isabel Burguete, Santiago V. Luis
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/a52609bd5e3c495d9e16c28d8b361915
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