MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA

Abstract. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established. For this purposes it was proposed to use the modified variant of ELISA allowed to det...

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Main Authors:	L. A. Kraeva, E. A. Alekseeva, G. Y. Tseneva, L. A. Lipatova, G. I. Bespalova
Format:	article
Language:	RU
Published:	Sankt-Peterburg : NIIÈM imeni Pastera 2014
Subjects:	diphtheria post vaccination immunity toxigenic strains Infectious and parasitic diseases RC109-216
Online Access:	https://doaj.org/article/a55f2e90463b4ee08e1527fc270c9ce1
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spelling	oai:doaj.org-article:a55f2e90463b4ee08e1527fc270c9ce12021-11-22T07:09:46ZMODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA2220-76192313-739810.15789/2220-7619-2012-4-729-734https://doaj.org/article/a55f2e90463b4ee08e1527fc270c9ce12014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/110https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established. For this purposes it was proposed to use the modified variant of ELISA allowed to detect both indices simultaneously. The formula of probable development of diphtheria in case of the close contact with patients or Corynebacterium diphtheriae bacteria carriers as well as determination of revaccination time have been proposed. The authors developed “The algorithm of population immunity control and assessment of non-susceptibility to diphtheria” and “The algorithm of micro biological testing of clinical samples for C. diphtheriae”.L. A. KraevaE. A. AlekseevaG. Y. TsenevaL. A. LipatovaG. I. BespalovaSankt-Peterburg : NIIÈM imeni Pasteraarticlediphtheriapost vaccination immunitytoxigenic strainsInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 2, Iss 4, Pp 729-734 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	diphtheria post vaccination immunity toxigenic strains Infectious and parasitic diseases RC109-216
spellingShingle	diphtheria post vaccination immunity toxigenic strains Infectious and parasitic diseases RC109-216 L. A. Kraeva E. A. Alekseeva G. Y. Tseneva L. A. Lipatova G. I. Bespalova MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
description	Abstract. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established. For this purposes it was proposed to use the modified variant of ELISA allowed to detect both indices simultaneously. The formula of probable development of diphtheria in case of the close contact with patients or Corynebacterium diphtheriae bacteria carriers as well as determination of revaccination time have been proposed. The authors developed “The algorithm of population immunity control and assessment of non-susceptibility to diphtheria” and “The algorithm of micro biological testing of clinical samples for C. diphtheriae”.
format	article
author	L. A. Kraeva E. A. Alekseeva G. Y. Tseneva L. A. Lipatova G. I. Bespalova
author_facet	L. A. Kraeva E. A. Alekseeva G. Y. Tseneva L. A. Lipatova G. I. Bespalova
author_sort	L. A. Kraeva
title	MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
title_short	MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
title_full	MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
title_fullStr	MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
title_full_unstemmed	MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
title_sort	modern approaches in complex laboratory testing for diphtheria
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2014
url	https://doaj.org/article/a55f2e90463b4ee08e1527fc270c9ce1
work_keys_str_mv	AT lakraeva modernapproachesincomplexlaboratorytestingfordiphtheria AT eaalekseeva modernapproachesincomplexlaboratorytestingfordiphtheria AT gytseneva modernapproachesincomplexlaboratorytestingfordiphtheria AT lalipatova modernapproachesincomplexlaboratorytestingfordiphtheria AT gibespalova modernapproachesincomplexlaboratorytestingfordiphtheria
_version_	1718418059251679232

MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA

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