Accounting for alignment uncertainty in phylogenomics.

Uncertainty in multiple sequence alignments has a large impact on phylogenetic analyses. Little has been done to evaluate the quality of individual positions in protein sequence alignments, which directly impact the accuracy of phylogenetic trees. Here we describe ZORRO, a probabilistic masking prog...

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Autores principales: Martin Wu, Sourav Chatterji, Jonathan A Eisen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/a59607bed321484f846adc80ab8fe34a
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