Functional Changes in the Gut Microbiome Contribute to Transforming Growth Factor β-Deficient Colon Cancer

ABSTRACT Colorectal cancer (CRC) is one of the most treatable cancers, with a 5-year survival rate of ~64%, yet over 50,000 deaths occur yearly in the United States. In 15% of cases, deficiency in mismatch repair leads to null mutations in transforming growth factor β (TGF-β) type II receptor, yet g...

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Bibliographic Details
Main Authors: Scott G. Daniel, Corbie L. Ball, David G. Besselsen, Tom Doetschman, Bonnie L. Hurwitz
Format: article
Language:EN
Published: American Society for Microbiology 2017
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Online Access:https://doaj.org/article/a5afe66dbbc845e3873a8028da059b02
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