Functional Changes in the Gut Microbiome Contribute to Transforming Growth Factor β-Deficient Colon Cancer
ABSTRACT Colorectal cancer (CRC) is one of the most treatable cancers, with a 5-year survival rate of ~64%, yet over 50,000 deaths occur yearly in the United States. In 15% of cases, deficiency in mismatch repair leads to null mutations in transforming growth factor β (TGF-β) type II receptor, yet g...
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Autores principales: | Scott G. Daniel, Corbie L. Ball, David G. Besselsen, Tom Doetschman, Bonnie L. Hurwitz |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2017
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Acceso en línea: | https://doaj.org/article/a5afe66dbbc845e3873a8028da059b02 |
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