Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia
Disease monitoring of chronic lymphocytic leukaemia (CLL) is a challenge. Here, the authors show that serial ctDNA analysis in 32 CLL patients allows monitoring of clonal dynamics over time, and identifies the emergence of genomic changes associated with Richter’s syndrome.
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Subjects: | |
Online Access: | https://doaj.org/article/a5d0115fb7e149b29d91aa033cf28281 |
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