Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1.
Cell-cell junctions are an integral part of epithelia and are often disrupted in cancer cells during epithelial-to-mesenchymal transition (EMT), which is a main driver of metastatic spread. We show here that Metastasis suppressor-1 (Mtss1; Missing in Metastasis, MIM), a member of the IMD-family of p...
Saved in:
Main Authors: | John C Dawson, Susann Bruche, Heather J Spence, Vania M M Braga, Laura M Machesky |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
|
Subjects: | |
Online Access: | https://doaj.org/article/a5e57de7038d49d480ef17bb33be33eb |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Rac1 and Rac3 GTPases regulate the development of hilar mossy cells by affecting the migration of their precursors to the hilus.
by: Roberta Pennucci, et al.
Published: (2011) -
Characterization of the erythrocyte GTPase Rac1 in relation to Plasmodium falciparum invasion
by: Silvio Paone, et al.
Published: (2020) -
The Small GTPase Rac1 Increases Cell Surface Stiffness and Enhances 3D Migration Into Extracellular Matrices
by: Tom Kunschmann, et al.
Published: (2019) -
Rac GTPase Signaling in Immune-Mediated Mechanisms of Atherosclerosis
by: Cadence F. Lee, et al.
Published: (2021) -
Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics
by: Valentina Zamboni, et al.
Published: (2018)