CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data

CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data

The control of off-target activity is a challenge for adapting CRISPR to therapeutic use. Here the authors present CRISPECTOR, a software tool to detect, evaluate and quantify editing activity, including translocations, from NGS data.

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Bibliographic Details
Main Authors: Ido Amit, Ortal Iancu, Alona Levy-Jurgenson, Gavin Kurgan, Matthew S. McNeill, Garrett R. Rettig, Daniel Allen, Dor Breier, Nimrod Ben Haim, Yu Wang, Leon Anavy, Ayal Hendel, Zohar Yakhini
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
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Online Access:https://doaj.org/article/a5eef4e669634506b9f9db24ef9fe0fe
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Internet

https://doaj.org/article/a5eef4e669634506b9f9db24ef9fe0fe

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