CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data
The control of off-target activity is a challenge for adapting CRISPR to therapeutic use. Here the authors present CRISPECTOR, a software tool to detect, evaluate and quantify editing activity, including translocations, from NGS data.
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Autores principales: | , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/a5eef4e669634506b9f9db24ef9fe0fe |
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