CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data

CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data

The control of off-target activity is a challenge for adapting CRISPR to therapeutic use. Here the authors present CRISPECTOR, a software tool to detect, evaluate and quantify editing activity, including translocations, from NGS data.

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Detalles Bibliográficos
Autores principales: Ido Amit, Ortal Iancu, Alona Levy-Jurgenson, Gavin Kurgan, Matthew S. McNeill, Garrett R. Rettig, Daniel Allen, Dor Breier, Nimrod Ben Haim, Yu Wang, Leon Anavy, Ayal Hendel, Zohar Yakhini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/a5eef4e669634506b9f9db24ef9fe0fe
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